Javier Carreras, Alberto Avenoza, Jesús H. Busto, and Jesús M. Peregrina
A novel azabicyclic amino acid was synthesized in both enantiopure forms. The ring-opening metathesis of methyl N-(tert-butoxycarbonyl)-7-azabicyclo[2.2.1]hept-2-ene-1-carboxylates was used as a method for accessing a new family of enantiopure proline analogues.
Synthesis 2010, 19, 3353; doi: 10.1055/s-0030-1257907